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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1673-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP1673-20 | 7 days | 20 µg | $290.00 | |||
| RCP1673-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | PNRC2 Human |
|---|---|
| Description | |
| Proline-Rich Nuclear Receptor Coactivator 2 Human Recombinant | |
| Accession (Primary) | Q9NPJ4 |
| Synonyms | |
| Podocalyxin, Podocalyxin-like protein 1, PC, PCLP-1. | |
| Introduction | |
| Podocalyxin (PODXL) is a greatly glycosylated transmembrane sialoprotein in the CD34 and endoglycan family. The PODXL protein is involved in the regulation of both adhesion and cell morphology and cancer progression. PODXL functions as an anti-adhesive molecule, which retains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Moreover, PODXL serves as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. | |
| Source | |
| HEK293 Cells | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| PODXL protein solution (1mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles. | |
| Purity | |
| Greater than 95% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| DGS -SPSPSPS PSQNATQTTT DSSNKTAPTP ASSVTIMATD TAQQSTVPTS KANEILASVK ATTLGVSSDS PGTTTLAQQV SGPVNTTVAR GGGSGNPTTT IESPKSTKSA DTTTVATSTA TAKPNTTSSQ NGAEDTTNSG GKSSHSVTTD LTSTKAEHLT TPHPTSPLSP RQPTSTHPVA TPTSSGHDHL MKISSSSSTV AIPGYTFTSP GMTTTLPSSV ISQRTQQTSS QMPASSTAPS SQETVQPTSP ATALRTPTLP ETMSSSPTAA STTHRYPKTP SPTVAHESNW AKCEDLETQT QSEKQLVLNL TGNTLCAGGA SDEKLISLIC RAVKATFNPA QDKCGIRLAS VPGSQTVVVK EITIHTKLPA KDVYERLKDK WDELKEAGVS DMKLGDQGPP EEAEDRFSMP- HHHHHH . | |
| Precautions | |
| PNRC2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9NPJ4 ) | |
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ADMEbio Team
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