| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1772-5 | 7 days | 5 µg | $120.00 |
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| RCP1772-20 | 7 days | 20 µg | $290.00 | |||
| RCP1772-1 | 7 days | 1 mg | $5,760.00 |
Product Overview | |
| Name | RAB5A Human |
|---|---|
| Description | |
| RAB5A Human Recombinant | |
| Accession (Primary) | P20339 |
| Synonyms | |
| Ras-related protein Rab-5B, RAB5B. | |
| Introduction | |
| Ras-related protein Rab-5B (RAB5B) belongs to the Rab family of small (monomeric) G proteins. RAB5B is involved in endocytosis and recycling of cell surface molecules. RAB5B interacts with RIN2 and RIN3, which regulate its function, possibly by acting as GEFs. Knockdown of RAB5B abolished group I metabotropic glutamate receptor (mGluR)-mediated neuroprotection. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The RAB5B solution (1 mg/ml), 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 20% glycerol and 0.2M NaCl. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS MTSRSTA RPNGQPQASK ICQFKLVLLG ESAVGKSSLV LRFVKGQFHE YQESTIGAAF LTQSVCLDDT TVKFEIWDTA GQERYHSLAP MYYRGAQAAI VVYDITNQET FARAKTWVKE LQRQASPSIV IALAGNKADL ANKRMVEYEE AQAYADDNSL LFMETSAKTA MNVNDLFLAI AKKLPKSEPQ NLGGAAGRSR GVDLHEQSQQ NKSQCCSN. | |
| Precautions | |
| RAB5A Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P20339 ) | |
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