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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1794-2 | 7 days | 2 µg | $120.00 |
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| RCP1794-10 | 7 days | 10 µg | $290.00 | |||
| RCP1794-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | RAET1G Human |
|---|---|
| Description | |
| Retinoic Acid Early Transcript 1G Human Recombinant | |
| Accession (Primary) | Q6H3X3 |
| Synonyms | |
| early transcript 1L, ULBP6, UL16-binding protein 6, RAET1L, retinoic acid early transcript 1L protein, retinoic acid early transcript 1L | |
| Introduction | |
| RAET1L plays a role as a stress-induced ligand for NKG2D receptor. Retinoic Acid Early Transcript 1L (RAET1L) is linked to the cell membrane by the GPI anchor. HCMV infection triggers RAET1L’sexpression but HCMV alters its function. HCMV-encoded UL16 glycoprotein retains RAET1L/ULBP6 inside the cells, preventing it from reaching the cell surface and being exposed to cells of the immune system. RAET1L has a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands. | |
| Source | |
| Sf9, Baculovirus cells. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| The RAET1L solution (1mg/ml) contains 10% glycerol and Phosphate-Buffered Saline (pH 7.4). | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| ADPRRDDPHS LCYDITVIPK FRPGPRWCAV QGQVDEKTFL HYDCGNKTVT PVSPLGKKLN VTMAWKAQNP VLREVVDILT EQLLDIQLEN YTPKEPLTLQ ARMSCEQKAE GHSSGSWQFS IDGQTFLLFD SEKRMWTTVH PGARKMKEKW ENDKDVAMSF HYISMGDCIG WLEDFLMGMD STLEPSAGAP LAMSSG HHHH HH | |
| Biological Activity | |
| Determined by its binding ability in a functional ELISA with Human KLRK1 (CAT# pro-2474). | |
| Precautions | |
| RAET1G Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q6H3X3 ) | |
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ADMEbio Team
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ADMEbio Team
