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RAP Rat

Receptor Associated Protein Rat Recombinant

 
Catalog #
RCP1807
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
RCP1807-5 7 days 5 µg $120.00
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RCP1807-20 7 days 20 µg $290.00
RCP1807-1 7 days 1 mg $4,480.00
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Product Overview

NameRAP Rat
Description
Receptor Associated Protein Rat Recombinant
Synonyms
KREV1, G-22K, C21KG, RAP1A, RAP1, Ras-related protein Rap-1A, GTP-binding protein smg p21A, Ras-related protein Krev-1.
Introduction
RAP1A is part of the family of RAS-related proteins which possess 50% amino acid identity with the classical RAS proteins and have various structural characteristics in common. RAP proteins differ from RAS proteins in their 61st amino acid, glutamine in RAS is replaced by threonine in RAP proteins. RAP1A induces morphological reversion of a cell line transformed by a Ras oncogene and counteracts the mitogenic function of Ras, since it can interact with Ras GAPs and RAF in a competitive manner.
Source
Escherichia Coli.
Physical Appearance
Sterile filtered colorless solution.
Formulation
0.25mg/ml solution containing 20mM Tris HCL pH-8.0, 5mM DTT, 0.2M NaCl & 40% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MREYKLVVLG SGGVGKSALT VQFVQGIFVE KYDPTIEDSY RKQVEVDCQQ CMLEILDTAG TEQFTAMRDL YMKNGQGFAL VYSITAQSTF NDLQDLREQI LRVKDTEDVP MILVGNKCDL EDERVVGKEQ GQNLARQWCN CAFLESSAKS KINVNEIFYD LVRQINRKTP VEKKKPKKKS C.
Precautions
RAP Rat is for research use only and not for use in diagnostic or therapeutic procedures.
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