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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1815-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP1815-25 | 7 days | 25 µg | $290.00 | |||
| RCP1815-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | RARRES2 Human |
|---|---|
| Description | |
| Retinoic Acid Receptor Responder 2 Human Recombinant | |
| Accession (Primary) | Q99969 |
| Synonyms | |
| Chemerin, TIG2, Tazarotene-induced gene 2 protein, Retinoic acid receptor responder protein 2, RAR-responsive protein TIG2, RARRES2, HP10433. | |
| Introduction | |
| RARRES2 is a secreted chemotactic protein that initiates chemotaxis through the ChemR23 G protein-coupled seven-transmembrane domain ligand. RARRES2 is upregulated by the synthetic retinoid tazarotene and found in many tissues. RARRES2 acts as an adipokine and is truncated on both termini from the proprotein. RARRES2 is structurally related to the cathelicidin precursors, cystatin C and kininogens. RARRES2 promotes calcium mobilization and chemotaxis of immature dendritic cells and macrophages. RARRES2 is secreted as a precursor of little biological activity, which requires proteolytic cleavage of its COOH-terminal domain to be exchangeed into a potent and highly specific agonist of ChemR23. | |
| Source | |
| HEK293. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| RARRES2 protein solution (0.5mg/ml) contains 10% glycerol & Phosphate buffered saline (pH7.4). | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| ELTEAQRRGL QVALEEFHKH PPVQWAFQET SVESAVDTPF PAGIFVRLEF KLQQTSCRKR DWKKPECKVR PNGRKRKCLA CIKLGSEDKV LGRLVHCPIE TQVLREAEEH QETQCLRVQR AGEDPHSFYF PGQFAFS HHH HHH . | |
| Precautions | |
| RARRES2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q99969 ) | |
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ADMEbio Team
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