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RCVRN Mouse

Recoverin Mouse Recombinant

 
Catalog #
RCP1838
Uniprot Id
P34057
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
RCP1838-2 7 days 2 µg $120.00
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RCP1838-10 7 days 10 µg $290.00
RCP1838-1 7 days 1 mg $8,320.00
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Product Overview

NameRCVRN Mouse
Description
Recoverin Mouse Recombinant
Accession (Primary)P34057
Synonyms
RD RNA binding protein, NELF-E, RD, D6S45, RDP, Major Histocompatibility Complex Gene RD, Negative Elongation Factor Polypeptide E, nuclear protein, RDBP.
Introduction
RDBP is a putative RNA binding protein. RDBP protein is one of the five components of the multisubunit NELF complex which collaborates with DSIF to repress RNA polymerase II elongation. Control of transcription elongation needs a complex interaction between positive transcription elongation factor b and negative transcription elongation factors, DSIF and NELF. DSIF and NELF, act as negative transcription elongation factors by increasing the time the polymerase spends at pause sites. RDBP has a functional RNA-binding domain, whose mutations impair transcription repression without affecting known protein-protein interactions.
Source
Escherichia Coli.
Physical Appearance
The RDBP is supplied as a sterile filtered clear solution.
Formulation
The RDBP protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0), 100mM NaCl, 2mM DTT and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
RDBP purity was found to be greater than 85% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MLVIPPGLSE EEEALQKKFN KLKKKKKALL ALKKQSSSST TSQGGVKRSL SEQPVMDTAT ATEQAKQLVK SGAISAIKAE TKNSGFKRSR TLEGKLKDPE KGPVPTFQPF QRSISADDDL QESSRRPQRK SLYESFVSSS DRLRELGPDG EEAEGPGAGD GPPRSFDWGY EERSGAHSSA SPPRSRSRDR SHERNRDRDR DRERDRDRDR DRDRERDRDR DRDRDRDRER DRDRERDRDR DREGPFRRSD SFPERRAPRK GNTLYVYGED MTPTLLRGAF SPFGNIIDLS MDPPRNCAFV TYEKMESADQ AVAELNGTQV ESVQLKVNIA RKQPMLDAAT GKSVWGSLAV QNSPKGCHRD KRTQIVYSDD VYKENLVDGF
Precautions
RCVRN Mouse is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( P34057 )

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