Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1853-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
|
||
| RCP1853-20 | 7 days | 20 µg | $290.00 | |||
| RCP1853-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | RGN Human |
|---|---|
| Description | |
| Regucalcin Human Recombinant | |
| Accession (Primary) | Q15493 |
| Synonyms | |
| Regulator of G-protein signaling 1, RGS1, B-cell activation protein BL34, Early response protein 1R20, 1R20, BL34, IER1, IR20. | |
| Introduction | |
| RGS1 belongs to the regulator of G-protein signaling family. The RGS1 protein is situated on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif termed the RGS domain. RGS1 diminish s the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and performing as a GTPase activating protein (GAP), boosting the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, creating inactive G-protein heterotrimers, thus terminating the signal. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| RGS1 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGSH MRAAAI STPKLDKMPG MFFSANPKEL KGTTHSLLDD KMQKRRPKTF GMDMKAYLRS MIPHLESGMK SSKSKDVLSA AEVMQWSQSL EKLLANQTGQ NVFGSFLKSE FSEENIEFWL ACEDYKKTES DLLPCKAEEI YKAFVHSDAA KQINIDFRTR ESTAKKIKAP TPTCFDEAQK VIYTLMEKDS YPRFLKSDIY LNLLNDLQAN SLK. | |
| Precautions | |
| RGN Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q15493 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
