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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1863-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP1863-25 | 7 days | 25 µg | $290.00 | |||
| RCP1863-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | RGS5 Human |
|---|---|
| Description | |
| Regulator of G-Protein Signaling 5 Human Recombinant | |
| Accession (Primary) | O15539 |
| Synonyms | |
| SLC42A5, CD240D, DIIIc, RhPI, RhII, Rh4. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Each mg was lyophilized with 1xPBS, 0.4% SDS and 4mM DTT. | |
| Stability | |
| Store lyophilized RhD at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Solubility | |
| It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it on cell culture. | |
| Background | |
| The Rh blood group system is one of the major blood group systems in humans and the D antigen is the main component of this system. D Antigen The presence of the D antigen on the surface of red blood cells indicates a positive Rh factor. Individuals with this antigen are classified as Rh-positive (Rh+), while those without it are Rh-negative (Rh-). Genetics The Rh factor is inherited in a Mendelian manner, with the D antigen being monitored by the RHD gene located on chromosome 1. The presence of the D allele (RHD) results in Rh positivity. Immunization Rh-negative individuals can develop antibodies against the D antigen if exposed to Rh-positive blood. In order to prevent such interaction, Rh-negative mothers are often given Rh immunoglobulin (Rho(D) immune globulin) during and after pregnancy. Clinical Significance The Rh D antigen is vital in blood transfusions and pregnancy. Rh incompatibility can occur when an Rh- mother carries an Rh+ fetus, which may lead to hemolytic disease of the newborn (HDN). Blood Transfusions Rh compatibility is very important in transfusions. Rh- individuals should receive Rh- blood to avoid an immune reaction. | |
| Precautions | |
| RGS5 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( O15539 ) | |
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ADMEbio Team
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