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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1877-5 | 7 days | 5 µg | $120.00 |
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| RCP1877-25 | 7 days | 25 µg | $290.00 | |||
| RCP1877-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | RLN3 Human |
|---|---|
| Description | |
| Relaxin-3 Human Recombinant | |
| Accession (Primary) | Q8WXF3 |
| Synonyms | |
| RNASE1, ribonuclease A family member 1, pancreatic, RAC1, RIB1, RNS1, ribonuclease pancreatic, HP-RNase, RIB-1, RNase UpI-1, RNase 1, Ribonuclease A, RNase A, Ribonuclease 1. | |
| Introduction | |
| Ribonuclease 1R (NASE1) is a small protein which is a part of pancreatic ribonuclease enzyme family. NASE1 has 4 disulfide bonds in its native state and cleaves speciallyafter pyrimidine nucleotides.Cleavage takes place in 2 steps: first, the 3’,5’-phosphodiester bond is cleaved to craete a 2’,3’-cyclic phosphodiester intermediate; than, the cyclic phosphodiester is hydrolyzed to a 3’-monophosphate. NASE1is activated the most with single stranded RNA.NASE1inhibited by alkylation of His12 and His119 and activated by potassium and sodium salts.NASE1hydrolyzes RNA from protein samples. | |
| Source | |
| HEK293 Cells. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The RNASE1 solution (1mg/ml) contains 10% Glycerol and Phosphate-Buffered Saline (pH 7.4). | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| KESRAKKFQR QHMDSDSSPS SSSTYCNQMM RRRNMTQGRC KPVNTFVHEP LVDVQNVCFQ EKVTCKNGQG NCYKSNSSMH ITDCRLTNGS RYPNCAYRTS PKERHIIVAC EGSPYVPVHF DASVEDST HH HHHH | |
| Biological Activity | |
| Specific activity is > 3 X 10^6 unit/mg. Defined by the amount of enzyme that hydrolyzes 1nmole of RNA per minute at 25 ˚ C. | |
| Precautions | |
| RLN3 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q8WXF3 ) | |
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ADMEbio Team
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ADMEbio Team
