| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP1989-5 | 7 days | 5 µg | $120.00 |
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| RCP1989-20 | 7 days | 20 µg | $290.00 | |||
| RCP1989-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | SAR1A Human |
|---|---|
| Description | |
| GTP-Binding Protein SAR1A Human Recombinant | |
| Accession (Primary) | Q9NR31 |
| Immunogen | |
| Anti-human SAR1B mAb, clone PAT1C7A, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human MRRF protein 1-198 amino acids purified from E. coli. | |
| Synonyms | |
| GTP-binding protein SAR1b, GTP-binding protein B, GTBPB, SAR1B, SARA2, SARB, ANDD, CMRD. | |
| Introduction | |
| SAR1B is a small GTPase that functions as a homodimer. GTP-Binding Protein SAR1B (SAR1b) is involved in transport from the endoplasmic reticulum to the Golgi apparatus and also in the selection of the protein cargo and the assembly of the COPII coat complex. The SAR1B protein is activated by the guanine nucleotide exchange factor PREB. SAR1B gene defects are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide. | |
| Applications | |
| The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| PAT1C7A. | |
| Ig Subclass | |
| Mouse IgG1 heavy chain and Kappa light chain. | |
| Purification Method | |
| SAR1B antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Stability / Shelf Life | |
| 12 months at -20°C. 1 month at 4°C. | |
| Precautions | |
| SAR1A Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9NR31 ) | |
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ADMEbio Team
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ADMEbio Team