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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2044-2 | 7 days | 2 µg | $120.00 |
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| RCP2044-10 | 7 days | 10 µg | $290.00 | |||
| RCP2044-1 | 7 days | 1 mg | $7,488.00 |
Product Overview | |
| Name | SERPINB2 Human |
|---|---|
| Description | |
| Serpin Peptidase Inhibitor, Clade B Member 2 Human Recombinant | |
| Accession (Primary) | P05120 |
| Synonyms | |
| Plasminogen activator inhibitor 2, PAI-2, Plasminogen activator inhibitor 2, SERPINB2, Serpin Peptidase Inhibitor, Clade B Member 2, His Tag, PLANH2, Monocyte Arg-serpin, Placental plasminogen activator inhibitor, Serpin B2, Urokinase inhibitor, HsT1201, PAI, PAI2. | |
| Introduction | |
| SERPINB2 is an inhibitory serpin produced primarily in keratinocytes, stimulated monocytes, and placental trophoblasts. SERPINB2 is found primarily as a 47 kDa non-glycosylated intracellular protein that is induced to be secreted as 60 kDa glycoprotein. The glycosylated and unglycosylated SERPINB2 are similarly effective as inhibitors of urokinase-type plasminogen activator (uPA), the only proven physiological target of SERPINB2. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| SERPINB2 protein solution (0.5mg/ml) containing Phosphate Buffered Saline (pH7.4), 30% glycerol and 1mM DTT. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 80.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS MEDLCVA NTLFALNLFK HLAKASPTQN LFLSPWSISS TMAMVYMGSR GSTEDQMAKV LQFNEVGANA VTPMTPENFT SCGFMQQIQK GSYPDAILQA QAADKIHSSF RSLSSAINAS TGNYLLESVN KLFGEKSASF REEYIRLCQK YYSSEPQAVD FLECAEEARK KINSWVKTQT KGKIPNLLPE GSVDGDTRMV LVNAVYFKGK WKTPFEKKLN GLYPFRVNSA QRTPVQMMYL REKLNIGYIE DLKAQILELP YAGDVSMFLL LPDEIADVST GLELLESEIT YDKLNKWTSK DKMAEDEVEV YIPQFKLEEH YELRSILRSM GMEDAFNKGR ANFSGMSERN DLFLSEVFHQ AMVDVNEEGT EAAAGTGGVM TGRTGHGGPQ FVADHPFLFL IMHKITNCIL FFGRFSSP. | |
| Precautions | |
| SERPINB2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P05120 ) | |
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ADMEbio Team
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