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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2064-2 | 7 days | 2 µg | $120.00 |
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| RCP2064-10 | 7 days | 10 µg | $290.00 | |||
| RCP2064-100 | 7 days | 100 µg | $1,920.00 |
Product Overview | |
| Name | SERTAD2 Human |
|---|---|
| Description | |
| SERTA Domain Containing 2 Human Recombinant | |
| Accession (Primary) | Q14140 |
| Synonyms | |
| 2PP2A, I2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA, Protein SET, HLA-DR-associated protein II, Inhibitor of granzyme A-activated DNase, Template-activating factor I, SET. | |
| Introduction | |
| SET is part of a complex localized to the endoplasmic reticulum however is found in the nucleus. SET inhibits apoptosis following attack by cytotoxic T lymphocytes and can also enhance DNA replication of the adenovirus genome. SET inhibits acetylation of nucleosomes, particularly histone H4, by histone acetylases (HAT). This inhibition is accomplished by masking histone lysines from being acetylated. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| The SET solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS MAPKRQS PLPPQKKKPR PPPALGPEET SASAGLPKKG EKEQQEAIEH IDEVQNEIDR LNEQASEEIL KVEQKYNKLR QPFFQKRSEL IAKIPNFWVT TFVNHPQVSA LLGEEDEEAL HYLTRVEVTE FEDIKSGYRI DFYFDENPYF ENKVLSKEFH LNESGDPSSK STEIKWKSGK DLTKRSSQTQ NKASRKRQHE EPESFFTWFT DHSDAGADEL GEVIKDDIWP NPLQYYLVPD MDDEEGEGEE DDDDDEEEEG LEDIDEEGDE DEGEEDEDDD EGEEGEEDEG EDD. | |
| Precautions | |
| SERTAD2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q14140 ) | |
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ADMEbio Team
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