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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2065-5 | 7 days | 5 µg | $120.00 |
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| RCP2065-20 | 7 days | 20 µg | $290.00 | |||
| RCP2065-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | SET Human |
|---|---|
| Description | |
| SET Human Recombinant | |
| Accession (Primary) | Q01105 |
| Immunogen | |
| Anti-human SETD7 mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human SETD7 amino acids 1-366 purified from E. coli. | |
| Synonyms | |
| Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7, EC 2.1.1.43, Histone H3-K4 methyltransferase, H3-K4-HMTase, SET domain-containing protein 7, Set9, SET7/9, SETD7. | |
| Introduction | |
| Set 7/9 is a histone methyltransferase (HMTase) that transfers methyl groups to Lys4 of histone H3, in complex with S-adenosyl-L-methionine (AdoMet). The methylation of lysine residues of histones plays a critical role in the regulation of chromatin structure and gene expression. Acetylation, phosphorylation and methylation of the amino-terminal tails of histone are thought to be involved in the regulation of chromatin structure and function. The enzymes identified in the methylation of specific lysine residue on histones belong to the SET family with just one exception. Set7/9, unlike most other SET proteins, is exclusively a mono-methylase. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, 10% Glycerol & 0.02% Sodium Azide. | |
| Applications | |
| SETD7 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 2,000. Recommended starting dilution is 1:1,000. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| Ps4E5AT. | |
| Ig Subclass | |
| Mouse IgG2b heavy chain and κ light chain. | |
| Purification Method | |
| SETD7 antibody was purified from hybridoma cell supernatant by protein-A affinity chromatography. | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Precautions | |
| SET Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q01105 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
