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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2074-2 | 7 days | 2 µg | $120.00 |
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| RCP2074-10 | 7 days | 10 µg | $290.00 | |||
| RCP2074-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | SFTPB Human |
|---|---|
| Description | |
| Surfactant Protein B Human Recombinant | |
| Accession (Primary) | P07988 |
| Synonyms | |
| Surfactant Protein D, SFTP4, Surfactant Pulmonary-Associated Protein D, Lung Surfactant Protein D, Collectin-7, COLEC7, PSP-D, SP-D, Surfactant-Associated Protein Pulmonary 4, Pulmonary Surfactant-Associated Protein D, Pulmonary Surfactant Apoprotein, Collectin 7, PSPD, SFTPD. | |
| Introduction | |
| Surfactant pulmonary-associated protein D (SFTPD) belongs to the collectin family of C-type lectins, which is synthesized in many tissues including respiratory epithelial cells in the lung, and contains one C-type lectin domain and one collagen-like domain. SFTPD has humoral molecules of the innate immune system, and is deemed a functional candidate in chronic periodontitis. Moreover, SFTPD is involved in the development of acute and chronic inflammation of the lung. A number of human lung diseases are characterized by decreased levels of bronchoalveolar SFTPD. SFTPD contributes to the lungs defense against inhaled microorganisms, organic antigens and toxins. SFTPD interacts with complexes such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. In addition, SFTPD participates in the extracellular reorganization or turnover of pulmonary surfactant. SFTPD binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| SFTPD protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.4M Urea. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 80.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS VASLRQQ VEALQGQVQH LQAAFSQYKK VELFPNGQSV GEKIFKTAGF VKPFTEAQLL CTQAGGQLAS PRSAAENAAL QQLVVAKNEA AFLSMTDSKT EGKFTYPTGE SLVYSNWAPG EPNDDGGSED CVEIFTNGKW NDRACGEKRL VVCEF. | |
| Precautions | |
| SFTPB Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P07988 ) | |
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