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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2093-1 | 7 days | 1 µg | $100.00 |
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| RCP2093-5 | 7 days | 5 µg | $260.00 | |||
| RCP2093-50 | 7 days | 50 µg | $1,920.00 |
Product Overview | |
| Name | SIGLEC5 Human |
|---|---|
| Description | |
| Sialic Acid Binding Ig Like Lectin 5 Human Recombinant | |
| Accession (Primary) | O15389 |
| Synonyms | |
| Sialic Acid Binding Ig Like Lectin 6, Obesity-Binding Protein 1, CD33 Antigen-Like 1, CDW327, CD33L1, CD33L, OBBP1, Sialic Acid Binding Ig-Like Lectin 6, Sialic Acid-Binding Ig-Like Lectin 6, CD327 Antigen, Siglec-6, CD33L2, OB-BP1, CD327, SIGLEC6. | |
| Introduction | |
| Sialic acid-binding Ig-like lectin 6 isoform 1 (SIGLEC6) is a member of immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC6 mediates sialic-acid dependent binding to cells and binds to alpha-2, 6-linked sialic acid. The SIGLEC6 protein localizes in numerous compartments such as membrane fraction, extracellular region and so on. The SIGLEC6 receptor binds sialyl-TN glycans and leptin. Placental expression SIGLEC6 is upregulated in preeclampsia. | |
| Source | |
| Sf9, Baculovirus cells. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| SIGLEC6 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| ADL QERRFQL EGPESLTVQE GLCVLVPCRL PTTLPASYYG YGYWFLEGAD VPVATNDPDE EVQEETRGRF HLLWDPRRKN CSLSIRDARR RDNAAYFFRL KSKWMKYGYT SSKLSVRVMA LTHRPNISIP GTLESGHPSN LTCSVPWVCE QGTPPIFSWM SAAPTSLGPR TTQSSVLTIT PRPQDHSTNL TCQVTFPGAG VTMERTIQLN VSYAPQKVAI SIFQGNSAAF KILQNTSSLP VLEGQALRLL CDADGNPPAH LSWFQGFPAL NATPISNTGV LELPQVGSAE EGDFTCRAQH PLGSLQISLS LFVHWKPEGR AGGV LEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSRDELTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGKHHH HHH . | |
| Precautions | |
| SIGLEC5 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( O15389 ) | |
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