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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2112-5 | 7 days | 5 µg | $120.00 |
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| RCP2112-20 | 7 days | 20 µg | $290.00 | |||
| RCP2112-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | SIX1 Human |
|---|---|
| Description | |
| SIX Homeobox 1 Human Recombinant | |
| Accession (Primary) | Q15475 |
| Synonyms | |
| Homeobox protein SIX6, Homeodomain protein OPTX2, Optic homeobox 2, Sine oculis homeobox homolog 6, SIX6, OPTX2, SIX9, OPTX2, MCOPCT2. | |
| Introduction | |
| SIX Homeobox 6 (SIX6) is a member of the SIX/Sine oculis homeobox family contains 1 homeobox DNA-binding domain. The SIX6 protein is essential in embryonic development by providing necessary instructions for the formation of the forebrain and eye development. SIX6 is expressed in the developing and adult retina, hypothalamic and the pituitary regions. SIX6 gene defects are the cause of microphthalmia isolated with cataract type 2. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| SIX6 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 40% glycerol, 5mM DTT and 2mM EDTA. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS MFQLPIL NFSPQQVAGV CETLEESGDV ERLGRFLWSL PVAPAACEAL NKNESVLRAR AIVAFHGGNY RELYHILENH KFTKESHAKL QALWLEAHYQ EAEKLRGRPL GPVDKYRVRK KFPLPRTIWD GEQKTHCFKE RTRNLLREWY LQDPYPNPSK KRELAQATGL TPTQVGNWFK NRRQRDRAAA AKNRLQQQVL SQGSGRALRA EGDGTPEVLG VATSPAASLS SKAATSAISI TSSDSECDI. | |
| Precautions | |
| SIX1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q15475 ) | |
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ADMEbio Team
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ADMEbio Team
