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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2162-5 | 7 days | 5 µg | $120.00 |
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| RCP2162-20 | 7 days | 20 µg | $290.00 | |||
| RCP2162-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | SNRNP70 Human |
|---|---|
| Description | |
| Small Nuclear Ribonucleoprotein 70kDa Human Recombinant | |
| Accession (Primary) | P08621 |
| Synonyms | |
| U1 small nuclear ribonucleoprotein A, U1 snRNP A, U1-A, U1A, SNRPA, Mud1. | |
| Introduction | |
| SNRPA associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is essential for splicing. The SNRPA protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and is involved in the coupling of splicing and polyadenylation. SNRPA binds stem loop II of U1 snRNA. SNRPA is the first snRNP to interact with pre-mRNA. This interaction is vital for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. | |
| Source | |
| Sf9 insect cells. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| SNRPA is supplied in 16mM HEPES buffer pH-7.6, 400mM NaCl and 20% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE | |
| Precautions | |
| SNRNP70 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P08621 ) | |
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ADMEbio Team
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