| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2175-1 | 7 days | 1 µg | $120.00 |
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| RCP2175-5 | 7 days | 5 µg | $290.00 | |||
| RCP2175-50 | 7 days | 50 µg | $1,920.00 |
Product Overview | |
| Name | SNRPE Human |
|---|---|
| Description | |
| Small Nuclear Ribonucleoprotein Polypeptide E Human Recombinant | |
| Accession (Primary) | P62304 |
| Synonyms | |
| Sm-F, Sm protein F, snRNP-F, SMF, PBSCF, Small Nuclear Ribonucleoprotein Polypeptide F. | |
| Introduction | |
| SNRPF is a member of the snRNP Sm proteins family. There are at least seven isoforms, E, F, G, D1, D2, D3 and B/B. This type of common proteins have a crucial part in the biogenesis of the snRNPs. Moreover, they represent the major targets for the so-called anti-Sm auto-antibodies that are diagnostic for systemic lupus erythematosus (SLE). SNRPF assist in the cytoplasmic construction of the UsnRNPs by binding to aconserved Sm site on UsnRNA and forming a stable snRNP core complex. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| The SNRPF protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 1mM EDTA , and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles. | |
| Purity | |
| Greater than 95% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MSLPLNPKPF LNGLTGKPVM VKLKWGMEYK GYLVSVDGYM NMQLANTEEY IDGALSGHLG EVLIRCNNVL YIRGVEEEEE DGEMRE | |
| Precautions | |
| SNRPE Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P62304 ) | |
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