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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2185-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| RCP2185-10 | 7 days | 10 µg | $290.00 | |||
| RCP2185-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | SOCS3 Human |
|---|---|
| Description | |
| Suppressor Of Cytokine Signaling 3 Human Recombinant | |
| Accession (Primary) | O14543 |
| Synonyms | |
| Superoxide dismutase [Cu-Zn], EC 1.15.1.1, SOD1, SOD, ALS, ALS1, IPOA. | |
| Introduction | |
| Human Cu/Zn Superoxide Dismutase (SOD1) catalyzes the reaction between superoxide anions and hydrogen to yield molecular oxygen and hydrogen peroxide. The enzyme protects the cell against dangerous levels of superoxide. SOD1 binds copper and zinc ions and is 1 of 3 isozymes accountable for destroying free superoxide radicals in the body. The encoded protein neutralizes supercharged oxygen molecules, which can damage cells if their levels are not controlled. Mutations in SOD1 cause a form of familial amyotrophic lateral sclerosis. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized from a 0.2 µm filtered concentrated (1mg/ml) solution in PBS, pH 7.4. | |
| Stability | |
| Lyophilized SOD although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution SOD should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| ATKAVCVLKG DGPVQGIINF EQKESNGPVK VWGSIKGLTE GLHGFHVHEF GDNTAGCTSA GPHFNPLSRK HGGPKDEERH VGDLGNVTAD KDGVADVSIE DSVISLSGDH CIIGRTLVVH EKADDLGKGG NEESTKTGNA GSRLACGVIG IAQ. | |
| Biological Activity | |
| The potency per mg was tested by Pyrogallic Acid method and was found to be more than 3,000 Units/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized SOD in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| SOCS3 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( O14543 ) | |
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ADMEbio Team
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