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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2219-5 | 7 days | 5 µg | $120.00 |
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| RCP2219-20 | 7 days | 20 µg | $290.00 | |||
| RCP2219-1 | 7 days | 1 mg | $5,760.00 |
Product Overview | |
| Name | SPG21 Human |
|---|---|
| Description | |
| Spastic Paraplegia 21 Human Recombinant | |
| Accession (Primary) | Q9NZD8 |
| Synonyms | |
| Transcription factor PU.1, 31 kDa-transforming protein, Transcription factor PU.1 isoform 1, SPI1, OF, PU.1, SFPI1, SPI-1, SPI-A. | |
| Introduction | |
| Spi-1 Proto-Oncogene, also known as SPI1, owns ETS-domain transcription factor which activates gene expression during myeloid and Blymphoid cell development. SPI1 binds to a purine-rich sequence called the PU-box which is located near the promoters of target genes, and regulates their expression. SPI1 binds RNA and modulate pre-mRNA splicing. SPI1 is also regulates alternative splicing of target genes. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| The SPI1 solution (0.25mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 85.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS MLQACKM EGFPLVPPQP SEDLVPYDTD LYQRQTHEYY PYLSSDGESH SDHYWDFHPH HVHSEFESFA ENNFTELQSV QPPQLQQLYR HMELEQMHVL DTPMVPPHPS LGHQVSYLPR MCLQYPSLSP AQPSSDEEEG ERQSPPLEVS DGEADGLEPG PGLLPGETGS KKKIRLYQFL LDLLRSGDMK DSIWWVDKDK GTFQFSSKHK EALAHRWGIQ KGNRKKMTYQ KMARALRNYG KTGEVKKVKK KLTYQFSGEV LGRGGLAERR HPPH. | |
| Precautions | |
| SPG21 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9NZD8 ) | |
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ADMEbio Team
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