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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2226-2 | 7 days | 2 µg | $120.00 |
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| RCP2226-10 | 7 days | 10 µg | $350.00 | |||
| RCP2226-0.1 | 7 days | 0.1 mg | $2,080.00 |
Product Overview | |
| Name | SPON1 Human |
|---|---|
| Description | |
| Recombinant Human Spondin-1 | |
| Accession (Primary) | Q9HCB6 |
| Synonyms | |
| Speckle-type POZ protein, HIB homolog 1, Roadkill homolog 1, SPOP, TEF2. | |
| Introduction | |
| Speckle-type POZ protein (SPOP) belongs to the Tdpoz family containing one N-terminal MATH (Meprin and TRAF homology) domain and one C-terminal BTB/POZ domain. SPOP inhibits IPF1/PDX1 transactivation of established target promoters, may be by recruiting a repressor complex. SPOP is involved in ubiquitinylation and protein degradation as a result of an interaction with CUL-3. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| SPOP is supplied as a sterile Filtered colorless solution. | |
| Formulation | |
| The SPOP solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 5mM DTT, 50% glycerol, 0.2M NaCl and 2mM EDTA. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MSRVPSPPPP AEMSSGPVAE SWCYTQIKVV KFSYMWTINN FSFCREEMGE VIKSSTFSSG ANDKLKWCLR VNPKGLDEES KDYLSLYLLL VSCPKSEVRA KFKFSILNAK GEETKAMESQ RAYRFVQGKD WGFKKFIRRD FLLDEANGLL PDDKLTLFCE VSVVQDSVNI SGQNTMNMVK VPECRLADEL GGLWENSRFT DCCLCVAGQE FQAHKAILAA RSPVFSAMFE HEMEESKKNR VEINDVEPEV FKEMMCFIYT GKAPNLDKMA DDLLAAADKY ALERLKVMCE DALCSNLSVE NAAEILILAD LHSADQLKTQ AVDFINYHAS DVLETSGWKS MVVSHPHLVA EAYRSLASAQ CPFLGPPRKR LKQS. | |
| Precautions | |
| SPON1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9HCB6 ) | |
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