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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2228-2 | 7 days | 2 µg | $120.00 |
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| RCP2228-10 | 7 days | 10 µg | $290.00 | |||
| RCP2228-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | SPRED1 Human |
|---|---|
| Description | |
| Sprouty-Related EVH1 Domain Containing 1 Human Recombinant | |
| Accession (Primary) | Q7Z699 |
| Synonyms | |
| Cornifin-B, 14.9 kDa pancornulin, Small proline-rich protein IB, SPR-IB, SPRR1B, SPRR1, GADD33, CORNIFIN. | |
| Introduction | |
| Small Proline-Rich Protein 1B (SPRR1B) is a keratinocyte protein which first appears in the cell cytosol, but eventually becomes cross-linked to membrane proteins by transglutaminase. SPRR1B is cross-linked to membrane proteins by transglutaminase leading to formation of an insoluble envelope. SPRR1B functions as both amine donor and acceptor in transglutaminase-mediated cross-linkage. SPRR1B is expressed in the course of differentiation in squamous tissues such as epidermis, esophagus, tongue or trachea. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| SPRR1B filtered (0.4 µm) and lyophilized from 0.5mg/ml in 0.05M phosphate buffer and 0.075M NaCl, pH 7.4. | |
| Stability | |
| Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MKHHHHHHA S SQQQKQPCTP PPQLQQQQVK QPCQPPPQEP CIPKTKEPCH PKVPEPCHPK VPEPCQPKVP EPCHPKVPEP CPSIVTPAPA QQKTKQK. | |
| Solubility | |
| It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. SPRR1B is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. | |
| Precautions | |
| SPRED1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q7Z699 ) | |
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ADMEbio Team
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ADMEbio Team
