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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2229-2 | 7 days | 2 µg | $120.00 |
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| RCP2229-10 | 7 days | 10 µg | $290.00 | |||
| RCP2229-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | SPRR1B Human |
|---|---|
| Description | |
| Small Proline-Rich Protein 1B Human Recombinant | |
| Accession (Primary) | P22528 |
| Synonyms | |
| Protein sprouty homolog 4, SPRY4, Sprouty Homolog 4, Spry-4, Protein sprouty homolog 4 isoform 2, Sprouty homolog 4 (Drosophila). | |
| Introduction | |
| Sprouty Homolog 4 (SPRY4) is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. SPRY4 is positioned upstream of RAS activation. SPRY4 protein functions include suppressing the EGFR-transduced MAPK signaling pathway as well as impairing the formation of GTP-Ras. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The SPRY4 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 85.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS MEPPIPQ SAPLTPNSVM VQPLLDSRMS HSRLQHPLTI LPIDQVKTSH VENDYIDNPS LALTTGPKRT RGGAPELAPT PARCDQDVTH HWISFSGRPS SVSSSSSTSS DQRLLDHMAP PPVADQASPR AVRIQPKVVH CQPLDLKGPA VPPELDKHFL LCEACGKCKC KECASPRTLP SCWVCNQECL CSAQTLVNYG TCMCLVQGIF YHCTNEDDEG SCADHPCSCS RSNCCARWSF MGALSVVLPC LLCYLPATGC VKLAQRGYDR LRRPGCRCKH TNSVICKAAS GDAKTSRPDK PF. | |
| Precautions | |
| SPRR1B Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P22528 ) | |
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ADMEbio Team
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