Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2231-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
|
||
| RCP2231-10 | 7 days | 10 µg | $290.00 | |||
| RCP2231-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | SPSB1 Human |
|---|---|
| Description | |
| SPRY Domain-Containing SOCS Cox Protein 1 Human Recombinant | |
| Accession (Primary) | Q96BD6 |
| Synonyms | |
| SPRY domain-containing SOCS box protein 2, SSB-2, Gene-rich cluster protein C9, SPSB2, GRCC9, SSB2, GRCC9. | |
| Introduction | |
| SPRY Domain-Containing SOCS Cox Protein 2 (SPSB2) belongs to a suppressor of cytokine signaling (SOCS) family, and is a member of the subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal SOCS box. SPSB2 is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. SPSB2 is apparent substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and ensuing proteasomal degradation of target proteins. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| SPSB2 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 85.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGSH MGQTAL AGGSSSTPTP QALYPDLSCP EGLEELLSAP PPDLGAQRRH GWNPKDCSEN IEVKEGGLYF ERRPVAQSTD GARGKRGYSR GLHAWEISWP LEQRGTHAVV GVATALAPLQ TDHYAALLGS NSESWGWDIG RGKLYHQSKG PGAPQYPAGT QGEQLEVPER LLVVLDMEEG TLGYAIGGTY LGPAFRGLKG RTLYPAVSAV WGQCQVRIRY LGERRAEPHS LLHLSRLCVR HNLGDTRLGQ VSALPLPPAM KRYLLYQ. | |
| Precautions | |
| SPSB1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q96BD6 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
