| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2298-5 | 7 days | 5 µg | $120.00 |
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| RCP2298-20 | 7 days | 20 µg | $290.00 | |||
| RCP2298-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | SURF2 Human |
|---|---|
| Description | |
| Surfeit-2 Human Recombinant | |
| Accession (Primary) | Q15527 |
| Synonyms | |
| Small VCP/P97-Interacting Protein, SVIP. | |
| Introduction | |
| Small VCP/p97-interacting protein (SVIP) is involved in various cellular processes, including membrane fusion and ubiquitin-dependent protein degradation. SVIP functions as an inhibitor of the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway. On the other hand, SVIP overexpression increased the levels of p62 protein and enhanced starvation-activated autophagy as well as stimulated sequestration of polyubiquitinated proteins and p62 in autophagosomes. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| The SVIP solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 2mM DTT. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 85.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS MGLCFPC PGESAPPTPD LEEKRAKLAE AAERRQKEAA SRGILDVQSV QEKRKKKEKI EKQIATSGPP PEGGLRWTVS. | |
| Precautions | |
| SURF2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q15527 ) | |
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ADMEbio Team
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