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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2348-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| RCP2348-10 | 7 days | 10 µg | $290.00 | |||
| RCP2348-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | TCP1 Human |
|---|---|
| Description | |
| T-Complex 1 Human Recombinant | |
| Accession (Primary) | P17987 |
| Immunogen | |
| Anti-human TDG mAb, clone PAT2F7A, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TDG protein 1-410 amino acids purified from E. coli. | |
| Synonyms | |
| Thymine-DNA Glycosylase, G/T Mismatch-Specific Thymine DNA Glycosylase, EC 3.2.2.29. | |
| Introduction | |
| Thymine-DNA glycosylase (TDG) is a member of the TDG/mug DNA glycosylase family. TDG is a nuclear protein that fixes G/T mismatches to G/C pairs by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired thymin. In addition, TDG removes uracil and 5-bromouracil from mispairings with guanine. The TDG enzyme has an essential role in cellular defense against genetic mutation triggered by the spontaneous deamination of 5-methylcytosine and cytosine. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide. | |
| Applications | |
| The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:250. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| PAT2F7A. | |
| Ig Subclass | |
| Mouse IgG 1 heavy chain and Kappa light chain. | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Stability / Shelf Life | |
| 12 months at -20°C. 1 month at 4°C. | |
| Precautions | |
| TCP1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P17987 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
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ADMEbio Team
