| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2394-0.1 | 7 days | 0.1 mg | $700.00 |
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| RCP2394-1 | 7 days | 1 mg | $1,100.00 | |||
| RCP2394-5 | 7 days | 5 mg | $3,200.00 |
Product Overview | |
| Name | TNC Rabbit |
|---|---|
| Description | |
| Skeletal Muscle Troponin-C Rabbit | |
| Accession (Primary) | P02586 |
| Immunogen | |
| r.Human TNF-a. | |
| Synonyms | |
| TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2. | |
| Introduction | |
| Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesisand viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells. Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer. | |
| Formulation | |
| 1mg/ml in PBS (after reconstitution). | |
| Solubility | |
| Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. | |
| Applications | |
| Direct ELISA, Western Blot, Immuneprecipitation, Intracellular staining. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| NYRhTNFa-E2. | |
| Ig Subclass | |
| Mouse IgG1. | |
| Purification Method | |
| ion exchange. | |
| Storage Procedures | |
| In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. | |
| Shipping Conditions | |
| Antibody is shipped lyophilized at ambient temperature. | |
| Titer | |
| In direct ELISA, using alkaline phosphatase goat anti-mouse Ig (Jackson Laboratories) 1:10,000 dilution will yield 0.7 O.D within 10 minutes. | |
| Note | |
| This antibody will bind very well to protein A in a buffer (PBS) containing high salt concentration (3M Nacl). | |
| Precautions | |
| TNC Rabbit is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P02586 ) | |
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ADMEbio Team
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ADMEbio Team