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TNNI2 Human

Troponin I Type 2 Human Recombinant

 
Catalog #
RCP2397
Uniprot Id
P48788
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
RCP2397-2 7 days 2 µg $120.00
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RCP2397-10 7 days 10 µg $290.00
RCP2397-1 7 days 1 mg $8,320.00
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Product Overview

NameTNNI2 Human
Description
Troponin I Type 2 Human Recombinant
Accession (Primary)P48788
Synonyms
AMCD2B, DA2B, FSSV, fsTnI, Troponin I, fast skeletal muscle, Troponin I, fast-twitch isoform.
Introduction
Troponin I, fast skeletal muscle (TNNI2), belongs to the troponin I gene family, and a part of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. TNNI2 is also suppresses tumor growth in human ovarian carcinoma. Mutations in TNNI2 cause myopathy and distal arthrogryposis type 2B.
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The TNNI2 solution (0.25mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 2M Urea, 20% glycerol and 0.2M NaCl.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 90% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGDEEKRNRA ITARRQHLKS VMLQIAATEL EKEESRREAE KQNYLAEHCP PLHIPGSMSE VQELCKQLHA KIDAAEEEKY DMEVRVQKTS KELEDMNQKL FDLRGKFKRP PLRRVRMSAD AMLKALLGSK HKVCMDLRAN LKQVKKEDTE KERDLRDVGD WRKNIEEKSG MEGRKKMFES ES.
Precautions
TNNI2 Human is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( P48788 )

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