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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2401-1 | 7 days | 1 µg | $120.00 |
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| RCP2401-5 | 7 days | 5 µg | $290.00 | |||
| RCP2401-50 | 7 days | 50 µg | $1,920.00 |
Product Overview | |
| Name | TNNI3 Human, (1-210) |
|---|---|
| Description | |
| Cardiac Troponin-I Human Recombinant (1-210 a.a.) | |
| Accession (Primary) | P19429 |
| Synonyms | |
| Troponin I cardiac muscle, Cardiac troponin I, TNNI3, TNNC1, CMH7, RCM1, cTnI, CMD2A, MGC116817. | |
| Introduction | |
| Troponin I (TnI), troponin T (TnT) and troponin C (TnC) form the troponin complex of the thin filaments of striated muscle. TnI is acts as the inhibitory subunit by blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains 3 genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TNNI3 gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in the TNNI3 gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| TNNI3 protein solution in PBS and 25mM arginine. | |
| Stability | |
| TNNI3 although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. | |
| Purity | |
| Protein is >95% pure as determined by 12% PAGE (coomassie staining). | |
| Precautions | |
| TNNI3 Human, (1-210) is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P19429 ) | |
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