| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2402-100 | 7 days | 100 µg | $330.00 |
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| RCP2402-500 | 7 days | 500 µg | $1,320.00 | |||
| RCP2402-1 | 7 days | 1 mg | $2,160.00 |
Product Overview | |
| Name | TNNI3 Human, His |
|---|---|
| Description | |
| Cardiac Troponin-I Human Recombinant, His Tag | |
| Accession (Primary) | P19429 |
| Synonyms | |
| Troponin I cardiac muscle, Cardiac troponin I, TNNI3, TNNC1, CMH7, RCM1, cTnI, CMD2A, MGC116817. | |
| Introduction | |
| Troponin I (TnI), troponin T (TnT) and troponin C (TnC) form the troponin complex of the thin filaments of striated muscle. TnI is acts as the inhibitory subunit by blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains 3 genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TNNI3 gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in the TNNI3 gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). | |
| Physical Appearance | |
| 2 vials of sterile filtered clear colorless solution. | |
| Formulation | |
| *Cardiac Troponin-I coating antibody (5mg/1ml) contains 50 mM Na-citrate, pH 6.0, 0.9 % NaCl and 0.095 % NaN3 as a preservative. * Cardiac Troponin-I conjugating antibody (1mg/1ml) contains 50 mM Na-citrate, pH 6.0, 0.9 % NaCl and 0.095 % NaN3 as a preservative. | |
| Stability | |
| Cardiac Troponin-I although stable at 4°C for 1 week, should be stored below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95%. | |
| Applications | |
| Lateral flow immunoassay. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Purification Method | |
| Purified monoclonal IgG by protein A chromatography. | |
| Precautions | |
| TNNI3 Human, His is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P19429 ) | |
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ADMEbio Team
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