| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2416-2 | 7 days | 2 µg | $120.00 |
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| RCP2416-10 | 7 days | 10 µg | $290.00 | |||
| RCP2416-100 | 7 days | 100 µg | $1,920.00 |
Product Overview | |
| Name | TPGS2 Human |
|---|---|
| Description | |
| Tubulin Polyglutamylase Complex Subunit 2 Human Recombinant | |
| Accession (Primary) | Q68CL5 |
| Synonyms | |
| TPI, TIM, Triosephosphate Isomerase 1. | |
| Introduction | |
| TPI1 is one of the triosephosphate isomerase family. TPI1 catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in TPI1 causes triosephosphate isomerase deficiency (TPI deficiency). TPI deficiency is an autosomal recessive disorder which is the most severe clinical disorder of glycolysis and is related to neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| The TPI1 protein solution (0.5mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0), 1mM DTT and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MAPSRKFFVG GNWKMNGRKQ SLGELIGTLN AAKVPADTEV VCAPPTAYID FARQKLDPKI AVAAQNCYKV TNGAFTGEIS PGMIKDCGAT WVVLGHSERR HVFGESDELI GQKVAHALAE GLGVIACIGE KLDEREAGIT EKVVFEQTKV IADNVKDWSK VVLAYEPVWA IGTGKTATPQ QAQEVHEKLR GWLKSNVSDA VAQSTRIIYG GSVTGATCKE LASQPDVDGF LVGGASLKPE FVDIINAKQ | |
| Precautions | |
| TPGS2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q68CL5 ) | |
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