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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2440-5 | 7 days | 5 µg | $120.00 |
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| RCP2440-20 | 7 days | 20 µg | $290.00 | |||
| RCP2440-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | TRIM28 Human |
|---|---|
| Description | |
| Tripartite Motif Containing 28 Human Recombinant | |
| Accession (Primary) | Q13263 |
| Synonyms | |
| E3 ubiquitin-protein ligase TRIM33, Ectodermin homolog, RET-fused gene 7 protein, Protein Rfg7, Transcription intermediary factor 1-gamma, TIF1-gamma, Tripartite motif-containing protein 33, TRIM33, KIAA1113, RFG7, TIF1G, ECTO, PTC7, TF1G, TIFGAMMA, TIF1GAMMA. | |
| Introduction | |
| Tripartite Motif Containing 33 (TRIM33) belongs to the tripartite motif family. This motif includes 3 zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM33 is assumed to be a transcriptional corepressor. TRIM33 functions as an E3 ubiquitin-protein ligase. TRIM33 also promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. In addition, TRIM33 inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Furthermore, TRIM33 has a role in the control of cell proliferation. | |
| Source | |
| Sf9 Insect Cells. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| TRIM33 is supplied in 20mM HEPES buffer pH-7.9, 550mM NaCl and 6M Urea. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 80.0% as determined by SDS-PAGE. | |
| Precautions | |
| TRIM28 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q13263 ) | |
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ADMEbio Team
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