| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2450-50 | 7 days | 50 µg | $1,200.00 |
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| RCP2450-100 | 7 days | 100 µg | $1,800.00 | |||
| RCP2450-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | TROVE2 Bovine, Biotin |
|---|---|
| Description | |
| TROVE Domain Family Member 2 Human Recombinant, Biotinlyated | |
| Synonyms | |
| 60 kDa SS-A/Ro ribonucleoprotein, 60 kDa ribonucleoprotein Ro, RoRNP, 60 kDa Ro protein, Ro 60 kDa autoantigen, TROVE domain family member 2, Sjoegren syndrome type A antigen, SS-A, Sjoegren syndrome antigen A2, TROVE2, RO60, SSA2, RO-60. | |
| Introduction | |
| Ro 60 kDa autoantigen is an RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. SSA2 may stabilize these RNAs from degradation. Sera taken from patients with Systemic Lupus Erythematosus (SLE) often contains antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign. | |
| Source | |
| Escherichia Coli. | |
| Formulation | |
| TROVE2 is supplied in 20mM HEPES buffer pH-8.0, 150mM NaCl, 1mM DTT and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as determined by SDS-PAGE. | |
| Immunological functions | |
| 1. Binds IgG-type human auto-antibodies. 2. Standard ELISA test (checkerboard analysis of positive/negative samples); line assay and immunodot test with positive/negative samples. | |
| Coating concentration | |
| 0.2-0.5 µg/ml (depending on the type of ELISA plate and coating buffer). Suitable for labeling of functional groups. | |
| Precautions | |
| TROVE2 Bovine, Biotin is for research use only and not for use in diagnostic or therapeutic procedures. | |
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ADMEbio Team
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