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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2463-2 | 7 days | 2 µg | $120.00 |
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| RCP2463-10 | 7 days | 10 µg | $290.00 | |||
| RCP2463-100 | 7 days | 100 µg | $1,920.00 |
Product Overview | |
| Name | TSR2 Human |
|---|---|
| Description | |
| TSR2 Human Recombinant | |
| Accession (Primary) | Q969E8 |
| Synonyms | |
| Tumor suppressing subtransferable candidate 4, Tumor-suppressing STF cDNA 4 protein, Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein, protein TSSC4. | |
| Introduction | |
| TSSC4 is a member of the TSSC4 family. TSSC4 protein is one of quite a few tumor-suppressing subtransferable fragments found in the imprinted gene domain of 11p15.5, a significant tumor-suppressor gene section. Modifications in this section are linked to the Beckwith-Wiedemann syndrome, rhabdomyosarcoma, Wilms tumor, adrenocortical carcinoma, and breast, ovarian, and lung cancer. TSSC4 takes part in malignancies and disease that include this section in addition to hematopoietic cell function. TSSC4 is broadly expressed in virtually all adult tissues, and is found in fetal liver, brain, lung and kidney. | |
| Source | |
| E.coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The TSSC4 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 200mM NaCl, 2mM DTT and 20% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGSH MAEAGT GEPSPSVEGE HGTEYDTLPS DTVSLSDSDS DLSLPGGAEV EALSPMGLPG EEDSGPDEPP SPPSGLLPAT VQPFHLRGMS STFSQRSRDI FDCLEGAARR APSSVAHTSM SDNGGFKRPL APSGRSPVEG LGRAHRSPAS PRVPPVPDYV AHPERWTKYS LEDVTEVSEQ SNQATALAFL GSQSLAAPTD CVSSFNQDPS SCGEGRVIFT KPVRGVEARH ERKRVLGKVG EPGRGGLGNP ATDRGEGPVE LAHLAGPGSP EAEEWGSPHG GLQEVEALSG SVHSGSVPGL PPVETVGFHG SRKRSRDHFR NKSSSPEDPG AEV | |
| Precautions | |
| TSR2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q969E8 ) | |
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ADMEbio Team
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