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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2479-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP2479-20 | 7 days | 20 µg | $290.00 | |||
| RCP2479-1 | 7 days | 1 mg | $5,760.00 |
Product Overview | |
| Name | TXN2 Human |
|---|---|
| Description | |
| Thioredoxin-2 Human Recombinant | |
| Accession (Primary) | Q99757 |
| Synonyms | |
| Thioredoxin-2, TRX2, TRX-2, TXN-2, TXN2. | |
| Introduction | |
| Thioredoxins are small disulphide-containing redox proteins (within the conserved Cys-Gly-Pro-Cys active site) that have been found in all the kingdoms of living organisms. Thioredoxin contains a single disulfide active site and serves as a general protein disulphide oxidoreductase. Thioredoxins are involved in the first unique step in DNA synthesis. It interacts with a broad range of proteins by a redox mechanism based on reversible oxidation of two cysteine thiol groups to a disulphide, accompanied by the transfer of two electrons and two protons. The net result is the covalent interconversion of a disulphide and a dithiol. It has been suggested that thioredoxin may catalyze the formation of correct disulfides during protein folding because of its ability to act as an efficient oxidoreductant. Trx also provides control over a number of transcription factors affecting cell proliferation and death through a mechanism referred to as redox regulation. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Lyophilized Powder. | |
| Formulation | |
| Each mg of TRX2 protein contains 20mM phosphate buffer pH 7.4. | |
| Stability | |
| TXN2 although stable at 4°C for 3 weeks, should be stored desiccated below -18°C. Please prevent freeze thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Biological Activity | |
| TXN2 activity is assayed by measuring the change in absorbance at 650 nm at 25°C The specific activity was found to be 3 units/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized TXN2 in sterile 18MΩ-cm H2O. | |
| Precautions | |
| TXN2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q99757 ) | |
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ADMEbio Team
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