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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2526-5 | 7 days | 5 µg | $120.00 |
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| RCP2526-20 | 7 days | 20 µg | $290.00 | |||
| RCP2526-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | USP14 Human |
|---|---|
| Description | |
| Ubiquitin Specific Peptidase 14 Human Recombinant | |
| Accession (Primary) | P54578 |
| Synonyms | |
| Ubiquitin Specific Peptidase 15, Ubiquitin Carboxyl-Terminal Hydrolase 15, Deubiquitinating Enzyme 15, Ubiquitin-Specific-Processing Protease 15, Ubiquitin Specific Protease 15, Ubiquitin Thiolesterase 15, KIAA0529, UNPH4, UNPH-2, EC 3.4.19.12, EC 3.1.2.15. | |
| Introduction | |
| USP15 belongs to the ubiquitin specific protease (USP) family of deubiquitinating enzymes which has a vital role in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. USP15 connects with the COP9 signalosome, and takes part in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms of this gene are known, and a pseudo gene of USP15 is sited on the long arm of chromosome 2. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| The USP15 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS MAEGGAA DLDTQRSDIA TLLKTSLRKG DTWYLVDSRW FKQWKKYVGF DSWDKYQMGD QNVYPGPIDN SGLLKDGDAQ SLKEHLIDEL DYILLPTEGW NKLVSWYTLM EGQEPIARKV VEQGMFVKHC KVEVYLTELK LCENGNMNNV VTRRFSKADT IDTIEKEIRK IFSIPDEKET RLWNKYMSNT FEPLNKPDST IQDAGLYQGQ VLVIEQKNED GTWPRGPSTP KKPLEQSC | |
| Precautions | |
| USP14 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P54578 ) | |
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