| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2545-5 | 7 days | 5 µg | $120.00 |
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| RCP2545-20 | 7 days | 20 µg | $290.00 | |||
| RCP2545-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | VBP1 Human |
|---|---|
| Description | |
| Von Hippel-Lindau Binding Protein 1 Human Recombinant | |
| Accession (Primary) | P61758 |
| Synonyms | |
| Vascular cell adhesion protein 1, V-CAM 1, INCAM-100, CD106, VCAM1, L1CAM, MGC99561, DKFZp779G2333. | |
| Introduction | |
| VCAM1 is a member of the Ig superfamily. It is a cell surface sialoglycoprotein expressed by cytokine activated endothelium. VCAM-1 contains 6 or 7 immunoglobulin domains, and is expressed on both large and small vessels only after the endothelial cells are stimulated by cytokines. The protein has a number of functions including the regulation of leukocyte migration, leukocyte endothelial cell adhesion and signal transduction and may play a role in a number of inflammatory diseases (artherosclerosis and rheumatoid arthritis). | |
| Source | |
| Escherichia Coli. | |
| Formulation | |
| VCAM1 is supplied in 10mM Tris-HCl (pH 8), 250mM NaCl, 0.5mM DTT, 1.5mM Cysteine, and 50% Glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 1-2 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as determined by SDS-PAGE. | |
| Applications | |
| VCAM1 can be used directly as a positive control in Western blotting, ELISA, immunoprecipitation and other immunological experiments. The biological activity of this product has not yet been tested. | |
| References | |
| Title: Novel Regulators of Fgf23 Expression and Mineralization in Hyp Bone Publication: Molecular Endocrinology 23.9 (2009): 1505-1518. Link: VCAM1 prospec publication | |
| Precautions | |
| VBP1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P61758 ) | |
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