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VNN1 Human

Vanin 1 Human Recombinant

 
Catalog #
RCP2554
Uniprot Id
O95497
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
RCP2554-2 7 days 2 µg $120.00
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RCP2554-10 7 days 10 µg $290.00
RCP2554-1 7 days 1 mg $8,320.00
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Product Overview

NameVNN1 Human
Description
Vanin 1 Human Recombinant
Accession (Primary)O95497
Synonyms
Vesicular overexpressed in cancer prosurvival protein 1, EGFR-coamplified and overexpressed protein, ECop, Glioblastoma-amplified secreted protein, Putative NF-kappa-B-activating protein 055N, VOPP1, ECOP, GASP, FLJ20532, DKFZp564K0822.
Introduction
Vesicular overexpressed in cancer prosurvival protein 1 (VOPP1) has been previously shown to be over-expressed in human glioblastoma multiform and squamous cell carcinoma. VOPP1 is a crucial regulator of NF-kappaB signaling, and this high-level, amplification-mediated VOPP1 expression, such as that occurring in tumors with amplified EGFR, might impact the resistance to apoptosis.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The VOPP1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 30% glycerol and 0.2M NaCl.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH M RRRMYPPPL IEEPAFNVSY TRQPPNPGPG AQQPGPPYYT DPGGPGMNPV GNSMAMAFQV PPNSPQGSVA CPPPPAYCNT PPPPYEQVVK AK.
Precautions
VNN1 Human is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( O95497 )

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