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VOPP1 Human

Vesicular Overexpressed in Cancer, Prosurvival Protein 1 Human Recombinant

 
Catalog #
RCP2555
Uniprot Id
Q96AW1
 
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RCP2555-2 7 days 2 µg $120.00
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RCP2555-10 7 days 10 µg $290.00
RCP2555-1 7 days 1 mg $8,320.00
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Product Overview

NameVOPP1 Human
Description
Vesicular Overexpressed in Cancer, Prosurvival Protein 1 Human Recombinant
Accession (Primary)Q96AW1
Synonyms
Charged multivesicular body protein 3, Chromatin-modifying protein 3, Neuroendocrine differentiation factor, Vacuolar protein sorting-associated protein 24, hVps24, CHMP3, CGI149, NEDF, VPS24, CGI-149.
Introduction
Charged multivesicular body protein 3 (VPS24/CHMP3) is a member of the vacuolar sorting protein family and function as chromatin modifying proteins. VPS24 links directly with CHMP2 and CHMP4 for the disassembly of ESCRT-III complex in an ATP-dependent manner. During HIV-1 infection, the virus uses the ESCRT-III complex to mediate budding and exocytosis of viral proteins. VPS24 overexpression strongly hinders HIV-1 release.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
VPS24 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGLFGKTQEK PPKELVNEWS LKIRKEMRVV DRQIRDIQRE EEKVKRSVKD AAKKGQKDVC IVLAKEMIRS RKAVSKLYAS KAHMNSVLMG MKNQLAVLRV AGSLQKSTEV MKAMQSLVKI PEIQATMREL SKEMMKAGII EEMLEDTFES MDDQEEMEEE AEMEIDRILF EITAGALGKA PSKVTDALPE PEPPGAMAAS EDEEEEEEAL EAMQSRLATL RS.
Precautions
VOPP1 Human is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( Q96AW1 )

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