| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2580-2 | 7 days | 2 µg | $120.00 |
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| RCP2580-10 | 7 days | 10 µg | $290.00 | |||
| RCP2580-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | WHSC2 Human |
|---|---|
| Description | |
| Wolf-Hirschhorn Syndrome Candidate 2 Human Recombinant | |
| Accession (Primary) | Q9H3P2 |
| Synonyms | |
| PYM, Partner of Y14 and mago, MGC13064, WIBG, BCGN Homolog, Protein wibg homolog. | |
| Introduction | |
| WIBG is a cooperateing partner of Mago-Y14. The Mago-Y14 heterodimer is a key protein of the EJC(exon junction complex) that is deposited on mRNAs as a consequence of splicing and influences postsplicing mRNA metabolism. WIBG is a cytoplasmic RNA-binding protein that is excluded from the nucleus by Crm1. WIBG relates directly with Mago-Y14 by means of its N-terminal domain. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| WIBG Human solution containing 20mM Tris pH-8, 0.1M NaCl & 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 85.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MEAAGSPAAT ETGKYIASTQ RPDGTWRKQR RVKEGYVPQE EVPVYENKYV KFFKSKPELP PGLSPEATAP VTPSRPEGGE PGLSKTAKRN LKRKEKRRQQ QEKGEAEALS RTLDKVSLEE TAQLPSAPQG SRAAPTAASD QPDSAATTEK AKKIKNLKKK LRQVEELQQR IQAGEVSQPS KEQLEKLARR RALEEELEDL ELGLLEHHHH HH. | |
| Precautions | |
| WHSC2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9H3P2 ) | |
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