| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2610-2 | 7 days | 2 µg | $120.00 |
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| RCP2610-10 | 7 days | 10 µg | $290.00 | |||
| RCP2610-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | ZFAND3 Human |
|---|---|
| Description | |
| Zinc Finger, AN1-Type Domain 3 Human Recombinant | |
| Accession (Primary) | Q9H8U3 |
| Synonyms | |
| Zinc Finger, AN1-Type Domain 5, Zinc Finger Protein 216, ZNF216, Zinc Finger A20 Domain-Containing Protein 2, Zinc Finger, A20 Domain Containing 2, ZA20D2, AN1-Type Zinc Finger Protein 5, ZFAND5A, AN1-type zinc finger protein 5, Zinc finger A20 domain-containing protein 2, Zinc finger protein 216. | |
| Introduction | |
| Zinc Finger, AN1-Type Domain 5, also known as ZFAND5 is implicated in protein degradation through the ubiquitin-proteasome system. ZFAND5 performs by anchoring ubiquitinated proteins to the proteasome and takes part in ubiquitin-mediated protein degradation during muscle atrophy. Furthemore, ZFAND5 plays a role in the regulation of NF-kappa-B activation as well as apoptosis. ZFAND5 inhibits NF-kappa-B activation as well as tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| ZFAND5 protein solution (0.5mg/ml) containing 20mM Phosphate buffer saline (pH 8.0), 30% glycerol and 1mM DTT. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 85.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS MAQETNQ TPGPMLCSTG CGFYGNPRTN GMCSVCYKEH LQRQQNSGRM SPMGTASGSN SPTSDSASVQ RADTSLNNCE GAAGSTSEKS RNVPVAALPV TQQMTEMSIS REDKITTPKT EVSEPVVTQP SPSVSQPSTS QSEEKAPELP KPKKNRCFMC RKKVGLTGFD CRCGNLFCGL HRYSDKHNCP YDYKAEAAAK IRKENPVVVA EKIQRI. | |
| Precautions | |
| ZFAND3 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9H8U3 ) | |
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