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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2624-1 | 7 days | 1 µg | $120.00 |
Select product before adding to cart
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| RCP2624-5 | 7 days | 5 µg | $290.00 | |||
| RCP2624-50 | 7 days | 50 µg | $1,920.00 |
Product Overview | |
| Name | ANG Human, Sf9 |
|---|---|
| Description | |
| ANG Human Recombinant, Sf9 | |
| Accession (Primary) | P03950 |
| Immunogen | |
| Anti-human ANGPTL3 mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with Recombinant human ANGPTL3 amino acids 243-460 purified from E. coli. | |
| Synonyms | |
| Angiopoietin 5, ANGPT5, ANGPTL3. | |
| Introduction | |
| Angiopoietin-like proteins ANGPTL3 and ANGPTL4 are secreted proteins mainly expressed in liver that have been demonstrated to regulate triglyceride metabolism by inhibiting the lipolysis of triglyceride-rich lipoproteins. ANGPTL3 is structurally similar to angiopoietins, which are vascular endothelial growth factors. The experimental results show that Angptl3 and Angptl4 function to regulate circulating triglyceride levels during different nutritional states and therefore play a role in lipid metabolism during feeding/fasting through differential inhibition of Lipoprotein lipase (LPL). Using deletion mutants of Angiopoietin 5 human, it was demonstrated that the N-terminal domain containing fragment - (17–207) and not the C-terminal fibrinogen-like domain containing fragment - (207–460) increased the plasma triglyceride levels in mice. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. | |
| Applications | |
| ANGPTL3 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 2,000. Recommended starting dilution is 1:1,000. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| P1D10AT. | |
| Ig Subclass | |
| Mouse IgG1 heavy chain and κ light chain. | |
| Purification Method | |
| ANGPTL3 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Stability / Shelf Life | |
| 12 months at -20°C. 1 month at 4°C. | |
| Precautions | |
| ANG Human, Sf9 is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P03950 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
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Thank you,
ADMEbio Team
