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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List |
|---|
Product Overview | |
| Name | BCAS2 Human |
|---|---|
| Description | |
| Breast Carcinoma Amplified Sequence 2 Human Recombinant | |
| Accession (Primary) | O75934 |
| Synonyms | |
| B-cell lymphoma 6 protein, BCL-6, Zinc finger protein 51, LAZ-3 protein, BCL-5, Zinc finger and BTB domain-containing protein 27, BCL6, BCL5, LAZ3, ZBTB27, ZNF51, BCL6A. | |
| Introduction | |
| Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt’s lymphomas and in nodular, lymphocyte predominant Hodgkin’s disease. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| Bcl-6 protein in 50mM Tris-HCl, pH7.5 and 10mM L-glutathione (reduced). | |
| Stability | |
| Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles. | |
| Precautions | |
| BCAS2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( O75934 ) | |
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