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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2634-2 | 7 days | 2 µg | $100.00 |
Select product before adding to cart
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| RCP2634-10 | 7 days | 10 µg | $260.00 | |||
| RCP2634-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | C9 Human |
|---|---|
| Description | |
| Complement Component 9 Human Recombinant | |
| Accession (Primary) | P02748 |
| Synonyms | |
| Calpain-1 catalytic subunit, EC 3.4.22.52, Calpain-1 large subunit, Calcium-activated neutral proteinase 1, Calpain mu-type, muCANP, Micromolar-calpain, Cell proliferation-inducing gene 30 protein, CANP 1, CAPN1, CANPL1, PIG30, CANP, muCL, CANP1. | |
| Introduction | |
| Calpain’s activity is attributed to two main isoforms: ?-calpain and m-calpain, which are ubiquitously, expressed proteases implicated in cellular migration, cell cycle progression, degenerative processes and cell death. These heterodimeric enzymes are composed of distinct catalytic subunits, encoded by Capn1 (?-calpain) or Capn2 (m-calpain), and a common regulatory subunit encoded by Capn4. CAPN1 is a calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of the substrates involved in cytoskeletal remodeling and signal transduction. CAPN1 is activated by micromolar concentrations of calcium and inhibited by calpastatin. | |
| Source | |
| Human Erythrocytes. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| 50mM imidazole-HCl, 100mM NaCl, 5mM EGTA, 1mM DTT and 10% sucrose. | |
| Stability | |
| CAPN1 although stable at 10°C for 1 week, should be stored below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Precautions | |
| C9 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P02748 ) | |
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ADMEbio Team
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ADMEbio Team
