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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List |
|---|
Product Overview | |
| Name | DnaK Mycobacterium Tuberculosis |
|---|---|
| Description | |
| DnaK (HSP70) Mycobacterium Tuberculosis Recombinant | |
| Accession (Primary) | P19993 |
| Synonyms | |
| DPP-IV, DPPIV, DPP4, DPP-4, Dipeptidyl Peptidase-IV, Dipeptidyl Peptidase-4, CD26, adenosine deaminase complexing protein 2, Dipeptidylpeptidase-IV, CD-26, ADABP, ADCP2, DPIV, TP103, DP-IV, DP-4, DP4. | |
| Introduction | |
| Group IB secretory phospholipase A2 (sPLA2-IB) mediates cell proliferation, cell migration, hormone release and eicosanoid production via its receptor in peripheral tissues. In the CNS, high-affinity binding sites of sPLA2-IB have been documented. sPLA2-IB induced neuronal cell death in a concentrationdependent manner depending on PGD2 metabolites, especially Delta12-PGJ2 that might mediate sPLA2-IB-induced apoptosis. The secretory PLA2 (sPLA2) family, in which 10 isozymes have been identified, consists of lowmolecular weight, Ca2+-requiring secretory enzymes that have been implicated in a number of biological processes, such as modification of eicosanoid generation, inflammation, and host defense. | |
| Source | |
| Human Placenta. | |
| Physical Appearance | |
| Filtered lyophilized (freeze-dried) powder. | |
| Formulation | |
| Each 70ng were lyophilized from 29.1 µl containing 2mM Tris-HCl, pH 8.0. | |
| Stability | |
| Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. | |
| Purity | |
| Greater than 95% as determined by SDS-PAGE. | |
| Biological Activity | |
| One unit is defined as the amount of enzyme which will hydrolyze 1 µm of H-Gly-Pro-pNA per 1min at 25°C, pH 7.8. | |
| Solubility | |
| Add deionized water to prepare a working stock solution of approximately 0.5mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. | |
| Human Virus Test | |
| The protein was prepared from tissue shown to be non-reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1and 2by FDA required tests. | |
| Specific Activity | |
| 13U/mg. | |
| Precautions | |
| DnaK Mycobacterium Tuberculosis is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P19993 ) | |
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ADMEbio Team
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ADMEbio Team
