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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2646-2 | 7 days | 2 µg | $350.00 |
Select product before adding to cart
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| RCP2646-5 | 7 days | 5 µg | $540.00 | |||
| RCP2646-10 | 7 days | 10 µg | $784.00 |
Product Overview | |
| Name | ERa Human |
|---|---|
| Description | |
| Estrogen Receptor alpha Human Recombinant | |
| Accession (Primary) | P03372 |
| Synonyms | |
| Excision Repair Cross-complementing rodent repair deficiency complementation group 1 (includes overlapping antisense sequence), RAD10, COFS4, UV20, DNA excision repair protein ERCC-1. | |
| Introduction | |
| ERCC1 polypeptide is essential for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which takes part in repair and mitotic intra-chromosomal recombination. NER mechanism includes dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1-XPF complex makes the 5' incision. Raised levels of ERCC1 were also found in cisplatin-resistant cells. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| ERCC1is supplied in 100 µg/ml in 50mM Tris-HCl (pH7.5) with 10mM L-glutathione (reduced). | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. | |
| Precautions | |
| ERa Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P03372 ) | |
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ADMEbio Team
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ADMEbio Team
