| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2665-100 | 7 days | 100 µg | $300.00 |
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| RCP2665-500 | 7 days | 500 µg | $1,200.00 | |||
| RCP2665-1000 | 7 days | 1000 µg | $1,920.00 |
Product Overview | |
| Name | MV Large Polymerase 58-149 a.a |
|---|---|
| Description | |
| Measles Virus Large Polymerase 58-149 a.a. Recombinant | |
| Synonyms | |
| GDF-8, MSTN, Growth Differentiation Factor 8, MSTN Muscle Hypertrophy. | |
| Introduction | |
| GDF8 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. | |
| Source | |
| Nicotiana benthamiana plant | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized from 1mg/ml solution in glycine 0.05M buffer at pH 8.5 and 100mM NaCl. | |
| Stability | |
| Lyophilized Myostatin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Myostatin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by Analysis by SDS-PAGE. | |
| Amino acid sequence | |
| HHHHHHDFGL DCDEHSTESR CCRYPLTVDF EAFGWDWIIA PKRYKANYCS GECEFVFLQK YPHTHLVHQA NPRGSAGPCC TPTKMSPINM LYFNGKEQII YGKIPAMVVD RCGCS | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Myostatin in sterile 18M?-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Serological Identification | |
| The protein was electrophoresed under reducing condition on a 15% SDS-polyacrylamide gel, transferred by electroblotting to a NC membrane and visualized by immune-detection with specific antibody Myostatin/ antiHis antibody (reducing conditions ~13kDa monomer and ~26kDa homodimers). | |
| Precautions | |
| MV Large Polymerase 58-149 a.a is for research use only and not for use in diagnostic or therapeutic procedures. | |
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