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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List |
|---|
Product Overview | |
| Name | PROC Human |
|---|---|
| Description | |
| Protein-c Human Recombinant | |
| Accession (Primary) | P04070 |
| Synonyms | |
| Mammotropin, Luteotropic hormone, Luteotropin, PRL. | |
| Introduction | |
| Prolactin is a neuroendocrine hormone synthesized primarily by the pituitary gland but also a variety of other cell types including the placenta, brain and uterus. Prolactin is secreted when eating, nursing, mating, estrogen treatment and during ovulation. Prolactin's primary role is to promote and maintain lactation but also plays a role in breast cancer development, regulation of reproductive function and immunoregulation. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The protein was lyophilized from a concentrated (1mg/ml) solution with 0.02% NaHCO3. | |
| Stability | |
| Lyophilized Prolactin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Prolactin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by gel filtration analysis. | |
| Amino acid sequence | |
| The a.a. sequence of the first 6 N-terminal a.a was found to be Ala-Leu-Pro-Ile-Cys-Pro. | |
| Biological Activity | |
| Chicken Prolactin was tested for its biological functionality in-vitro by inducing proliferation of Nb2 cells or Baf/3 cells that were stably transfected with Chicken Prolactin receptors. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Prolactin in sterile 0.4% NaHCO3 pH-8.5, not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| PROC Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P04070 ) | |
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