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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List |
|---|
Product Overview | |
| Name | SERPINA6 Mouse |
|---|---|
| Description | |
| Serpin Peptidase Inhibitor, Clade A Member 6 Mouse Recombinant | |
| Accession (Primary) | Q06770 |
| Synonyms | |
| PAI-1, PAI1, PLANH1, SERPINE1, PAIE, PLASMINOGEN ACTIVATOR INHIBITOR, BETA-MIGRATING ENDOTHELIAL-CELL-DERIVED TYPE. | |
| Introduction | |
| Plasminogen activator inhibitor-1 is the principal inhibitor of tissue plasminogen activator(tPA) and urokinase(uPA), the activators of plasminogenand hence fibrinolysis(the physiological breakdown of blood clots). It is a serine protease inhibitor(serpin) protein (SERPINE1). The other PAI, plasminogen activator inhibitor-2(PAI-2) is secreted by the placentaand only present in significant amounts during pregnancy. In addition, protease nexinacts as an inhibitor of tPA and urokinase. PAI-1, however, is the main inhibitor of the plasminogen activators. | |
| Physical Appearance | |
| Sterile Filtered clear colorless solution. | |
| Formulation | |
| 0.05M sodium phosphate 0.1M NaCl and 1mM EDTA (pH 6.6). | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Precautions | |
| SERPINA6 Mouse is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q06770 ) | |
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