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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP2695-2 | 7 days | 2 µg | $450.00 |
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| RCP2695-5 | 7 days | 5 µg | $850.00 | |||
| RCP2695-10 | 7 days | 10 µg | $1,200.00 |
Product Overview | |
| Name | SOX9 Human |
|---|---|
| Description | |
| SOX9 Human Recombinant | |
| Accession (Primary) | P48436 |
| Synonyms | |
| Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE, CD254, Tnfsf11, Opgl, Rankl, Trance | |
| Introduction | |
| Soluble RANK Ligand or type II membrane protein, is part of the TNF proteins family. RANKL has been found to have an effect on the immune system and regulates bone regeneration and remodeling. This protein regulates cell apoptosis, bunds to OPG protein (osteoprotegerin), cell proliferation regulator and acts as a ligand for RANK receptor. The protein is found to be expressed in various tissues such as thymus, colon, liver, skeletal muscle, osteoblast etc. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The sRANKL solution (1mg/ml) contains 0.1M NaCl and Tris-Hcl buffer (pH8.5). | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MKPEAQPFAH LTINAASIPS GSHKVTLSSW YHDRGWAKIS NMTLSNGKLR VNQDGFYYLY ANICFRHHET SGSVPTDYLQ LMVYVVKTSI KIPSSHNLMK GGSTKNWSGN SEFHFYSINV GGFFKLRAGE EISIQVSNPS LLDPDQDATY FGAFKVQDID | |
| Biological Activity | |
| Determined by osteoclast differentiation assay using RAW 264.7 mouse monocyte/macrophage cells. ED50 range for this is ≤ 2 ng/ml. | |
| Precautions | |
| SOX9 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P48436 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
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ADMEbio Team
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ADMEbio Team
